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Updates:

Target selection 
2007-03-07

Progress report 
2007-08-14
 

psi-big4 >  progress >  overview


 

Progress at PSI

Overview

Over 2500 experimental structures have been determined in a little over 7 years of protein structure initiative (PSI). About 82% of those structures originated from one of the 4 large-scale centers (BIG4) and over 55% of those were determined over the last 3 years. The BIG4 consortia continue to produce largely novel structures with very high modeling leverage.

 

PDB deposition statistics

BIG4 ALL-PSI
This month 2727
Last one year (starting 2007-11-26) 668680
This grant year (starting 2008-07-01) 254256
PSI-2 19672108
PSI-1+PSI-2 28433455

 

Numbers of experimental structures from PSI

 

Target status from TargetDB (since September 1, 2000)

Status Number of targets
Cloned 101762
Expressed 69145
Soluble 21747
Purified 20898
Crystallized 7660
Crystal Structure 2492
NMR Structure 270
Crystal Structure + NMR Structure 2762
Targets in PDB* 3058

*note that the number of targets with experimental structures is typically smaller than the number of PDB depositions from PSI (see above), as there can be multiple redundant structures for the same target.

  

Protein structures and families targeted by PSI-2

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